cholerous noun3 •(no longer used) Angry or irritable; cholericA cholerous soldier, jealous of his rights, struck the vase with his axe, exclaiming that the king had no right to more than fell to his allotment. — 1830 •(no longer used) Of or related to choler, yellow bile; cholericWhich will accompanied be with flegmatick and cholerous humours. — 1658 •(no longer used) Afflicted or contaminated with cholera.Persons who became ill, soon after being exposed to the influences of an atmosphere supposed to be impregnated with cholerous exhalations. — 1833 formscholerouses