chalice /ˈt͡ʃæl.ɪs/noun 2forms 1phrases 1 noun2 •A large drinking cup, often having a stem and base and used especially for formal occasions and religious ceremonies.[W]e but teach / Bloody Instructions, which, being taught, returne / To plague th' Inuentor. This euen-handed Iustice / Commends th' Ingredience of our poyson'd Challice / To our owne lips. — 1606 •A kind of water-cooled pipe for smoking cannabis. formschalices Phrases with chalice poisoned chaliceSomething which is initially regarded as advantageous but which is later recognized to be disadvantageous or harmful; an apparently beneficial or benign instrument or scheme for causing death or harm.