cascara sagrada UK /kaˌskɑː.ɹə səˈɡɹɑː.də/US /kæˌskɛɹ.ə səˈɡɹɑ.də/ noun2 •The tree from which cascara is obtained (Rhamnus purshiana), native to western North America. •A purgative made from the dried bark of an American buckthorn.