cabin fever noun2 •A condition of restlessness and irritability caused by being in a confined space.Some residents of Alaska suffer from cabin fever when they remain indoors throughout the long, snowy winters. •(no longer used) Typhus.The certain consequence is the low typhus or cabin fever, which at all times, and at this present moment, exists in Ireland to a degree, that in any other country would create a serious alarm. — 1820