bitter melon /ˈbɪtəɹ ˈmɛlən/ noun4 •A vine, Momordica charantia, which produces a bitter yet edible fruit.Bees often convey the pollen from the blossoms of a bitter melon vine to those of a sweet variety and completely change the character and flavor of its fruit. — 1896 •The fruit of the bitter melon vine. •The colocynth, Citrullus colocynthis. •(Australia) A similar fruit-bearing vine, Citrullus lanatus (Citroides Group). formsbitter melons