biomarker UK /ˈbaɪəʊˌmɑːkə/US /ˈbaɪoʊˌmɑɹkɚ/ noun2 •A substance used as an indicator of a biological state, most commonly disease.The goal of combining biomarkers is usually to increase the predictive power beyond that afforded by an individual molecular biomarker. — 2017 •Any measurable phenomenon that indicates the presence of life. formsbiomarkers