big girl noun4 •(informal) An older girl; a girl who is no longer an infant; a female child considered mature enough for a specified purpose.You can tie your own shoelaces – you're a big girl now. •(informal) An adult woman; a woman behaving as a responsible adult.Just put on your big-girl panties and make a choice. •A woman who is overweight.I was surprised he didn't take the straight line Camryn fed him about "Do you like big girls?" — 1999 •(informal, offensive) A timid, weak or effeminate boy or man.Stop crying, you big girl! formsbig girls