big-endian adjective2 •Storing the most significant byte of a multibyte number at a lower address than the least significant byte; that is, "big end" first.Most big Unix machines are big-endian, but Intel x86 machines and older Digital machines are little-endian. — 1999 •Transmitting the most significant byte of a multibyte number before transmitting the least significant byte; that is, "big end" first.