astaghfirullah /ˌæs.tæɡ.fɪ.ɹəˈlɑː/ exclamation3 •A short prayer of redemption; I seek forgiveness from Allah; God forgive me. •An expression of guilt or shame.I should not have done that, astaghfirullah. •(slang) An expression of disbelief, disapproval, surprise, shock, etc.Astaghfirullah! Look at the state of your room.