antipyretic /ˌæntɪpaɪˈɹɛtɪk/adjective 1noun 1forms 1 adjective1 •That reduces fever.The antipyretic action of AVP is limited mainly to its action in a precise location in the ventral septum, though there is some evidence for a similar action in the medial amygdala. — 1999 noun1 •A medicine that reduces fever; a febrifuge. formsantipyretics