androstenedione UK /ˌan.dɹɒ.stiːnˈdʌɪ.əʊn/US /ˌæn.dɹəˌstinˈdaɪˌoʊn/ noun1 •A steroid sex hormone C₁₉H₂₆O₂ that is secreted by the testes, ovaries, and adrenal cortex and is an intermediate in the biosynthesis of testosterone and estrogen. formsandrostenediones