anaphylaxis /ˌænəfɪˈlæksɪs/ noun2 •A severe and rapid systemic allergic reaction to an allergen, causing a constriction of the trachea, preventing breathing; anaphylactic shock.He said a bite could send someone into anaphylaxis, which is a narrowing of the airways and lowering of blood pressure, within minutes. — 2025 •Extreme sensitivity to a substance such as a foreign protein or drug. formsanaphylaxes