amnion UK /ˈæm.nɪ.ɒn/US /ˈæm.ni.ɑːn/ noun1 •The innermost membrane of the fetal membranes of reptiles, birds, and mammals; the sac in which the embryo is suspended.He never seemed to mind, and after a while, she no longer felt self-conscious about languishing in the amnion of his office. — 2022 formsamnia · amnions