AIDS /eɪdz/noun 1adjective 1forms 2 noun1 •a disease, caught through blood or sex, that leaves the body too weak to keep other diseases awayPatients with AIDS become highly susceptible to infection by intracellular microbes normally contained by T cells (Fig. 4.8). — 2007 adjective1 •(vulgar, offensive) Extremely annoying or frustrating.Dude, this game is so fucking AIDS. formsmore AIDS · most AIDS