adverse /ˈæd.və(ɹ)s/ adjective3 •Unfavorable; antagonistic in purpose or effect; hostile; actively opposing one's interests or wishes; contrary to one's welfare; acting against; working in an opposing direction.Happy were it for us all if we bore prosperity as well and wisely as we endure an adverse fortune. — 1829 •Opposed; contrary; opposing one's interests or desire.adverse circumstances •Opposite; confronting.Calpe's adverse height / […] must greet my sight — 1809 formsadverser · more adverse · adversest · most adverse