80s noun[plural only]2 •A range of the numbers eighty (80) to eighty-nine (89).Many of his friends are joining a burgeoning international community of elderweds, or those who marry in their 60s, 70s or even 80s. — 2002 •The decade of the 1980s.It was cocaine. I snorted Blow a couple of times. It was the perfect 80s drug after all. — 2014