woe is me UK /ˌwəʊ ɪz ˈmiː/US /ˌwoʊ ɪz ˈmi/ exclamation1 •(humorous) Used to show that the speaker feels distress or misery; humorous use usually also signals self-awareness regarding excessive self-pity.Blasted with extasie. Oh, woe is me, T'haue seene what I haue seene: see what I see. — 1599