wipe off verb4 •To remove (something such as dirt) by wiping. •To clean (something), removing any dirt from it, by wiping it.The countertop is dirty. Please wipe it off. •(slang) To remove semen off from the buttocks of a sexual partner after doing anal sex. •(figurative) To destroy completely, leaving no trace.Wipe that smile off your face!Wipe his data off the computer. formswiped off · wiping off · wipes off