whooping cough UK /ˈhuːpɪŋ ˌkɒf/US /ˈhuːpɪŋ ˌkɔf/ noun1 •A contagious disease of the respiratory system that usually affects children caused by the bacterium Bordetella pertussis, the advanced stage of which is characterised by spasms of coughing followed by a whooping sound during the intake of breath. formswhooping coughs