who cares phrase2 •(informal) A reply to an unimportant or irrelevant statement, indicating indifference on the part of the speaker. •(informal) A reply that dismisses the importance of another speaker's immediately preceding statement.It makes no difference if you fall on the whirl. Who cares? And when you are through dancing you can go out to the faucet and get yourself a drink—provided the water hasn't been turned off. — 1922