vampire facial noun1 •(slang) The combination of facial microneedling with the use of platelet-rich plasma (PRP) derived from the patient's own blood, thought to contain growth factors that increase collagen production.At least three women were infected with H.I.V. during cosmetic “vampire facial” procedures at an unlicensed spa in Albuquerque, federal officials said Thursday. — 2024 formsvampire facials