upend

verb4

1. •
   To end up; to set on end.
2. •
   (figurative) To destroy, invalidate, overthrow, or defeat.

   • The scientific evidence upended the popular myth.
3. •
   (figurative) To affect or upset drastically.

   • By the middle of March 2020, the COVID-19 pandemic upended normal life for virtually all Americans.
4. •
   To tip or turn over.

   • When he upended the bottle of water over his sleeping sister, the lid popped off and surprised them both.