Ts and blues

noun[plural only]1

1. •
   (informal) The combination of the drugs pentazocine (an opioid analgesic) and tripelennamine (an antihistamine), used for recreational purposes due to its euphoric effect in the 1970s and 1980s.

   • […] was usually combined with the antihistamine tripelennamine (“Ts and Bs” or “Ts and Blues” pattern of combined intravenous drug abuse). — 1990