tropomyosin UK /ˌtɹəʊ.pəʊˈmʌɪ.əs.ɪn/US /ˌtɹɑp.əˈmaɪ.əs.ɪn/ noun1 •A protein involved in muscle contraction and related to myosin, and occurs together with troponin in the thin filaments of muscle tissue. formstropomyosins