tranquilize /ˈtɹeɪ̯ŋkwɪlaɪ̯z/ verb4 •To calm (a person or animal) or put them to sleep using a tranquilizer dart.The escaped lion was finally tracked down, tranquilized, and safely returned to the zoo. •To dart (a person or animal) with a sedativeThe bear should go down several minutes after being tranquilized. •(literary) To make (something or someone) tranquil.[…] with words of sweetest kindness and consolation, he soothed and tranquilised me. — 1779 •(no longer used, rare) To become tranquil. formstranquilized · tranquilizing · tranquilizes