streptokinase UK /ˌstɹɛp.tə(ʊ)ˈkʌɪ.neɪz/US /ˌstɹɛp.toʊˈkaɪ.neɪs/ noun1 •An enzyme produced by some streptococci which is involved in breaking down red blood cells by activating plasminogen to produce plasmin. It is used to treat blood clots and inflammation. formsstreptokinases