shit up verb2 •(slang, vulgar) To cover or smear with excrement.To entice the screw into the best position to be shitted up the trick was to ask them to open a door on the landing. Keith was in his cell, conned the screw to the top of the stairs and whooshhhhhh!!! — 2006 •(slang, vulgar) To mess up; to ruin.They just go on shitting up the world and feel no responsibility for their character or anything they do. — 1991 formsshat up · shitted up · shitting up · shits up