run with verb4 •(informal) To follow something through to completion or realization.3M's culture and its organizational structure are all directed to encouraging its people to take an idea and run with it. — 2006 •(informal) To take an incomplete or inadequate (plan, text, etc.) and develop it further, often with the implication of carelessness.They took this three-second sound bite and ran with it to try to smear me. •(informal) To be a member of (a gang, hooligan firm, etc.); to associate with a, typically disreputable, individual or group.For about three years, I ran with several different gangs. — 2011 •To be streaming with a fluid.After a long run, his face was running with sweat.The streets were running with rain water. formsran with · running with · runs with