run up in verb1 •(slang, vulgar) To have sexual intercourse with, especially in a non-romantic wayI know a dude named Jimmy, used to run up in me Night time pissy drunk off the Henny and Rémy I didn't mind it, when he fucked me from behind it Felt fine, 'specially when he used to grind it — 1996 formsran up in · running up in · runs up in