roofie /ˈɹuː.fi/verb 2noun 2forms 4 verb2 •(slang) To put roofies in; to spike with roofies.Someone roofied her drink, but she found out and poured it away. •(slang) To cause someone to (usually unknowingly) ingest roofies.Melody figured roofying him was the only way she could get him to her guest room, for the intimate photos she planned to take. — 2012 noun2 •(slang) Synonym of rohypnol: flunitrazepam, a hypnotic drug (sleeping pill), sometimes used as a date rape drug.Since 17, been countin' Ms, my bank account's on Goofy / They say Cosby gave em roofies, now who know what the truth is? — 2017 •(slang) Synonym of date rape drug. formsroofied · roofieing · roofying · roofies