put up one's dukes verb2 •To raise one's clenched fists in front of one's body and stand in a threatening or defiant manner, in preparation for a fistfight. •To take firm action or to show oneself to be committed to such action, as when competing in a sporting event or other contest.Well you're a real tough cookie with a long history Of breaking little hearts like the one in me That's okay, let's see how you do it Put up your dukes and let's get down to it — 1980 formsputting up one's dukes · puts up one's dukes