protagonist UK /pɹəˈtæɡ.ə.nɪst/US /pɹoʊˈtæɡ.ə.nɪst/ noun3 •The main character, or one of the main characters, in any story, such as a literary work or drama. •A leading person in a contest; a principal performer. •(nonstandard) An advocate or champion of a cause or course of action. formsprotagonists