polytetrafluoroethylene UK /ˌpɒlitɛtɹəˌflɔːɹəʊˈɛθɪliːn/US /ˌpɑlitɛtɹəˌflɔɹoʊˈɛθɪlin/ noun1 •A tough synthetic resin used to make seals and bearings and to create a nonstick coating on cooking utensils. formspolytetrafluoroethylenes