piss off verb 2exclamation 1forms 3 verb2 •(informal, vulgar) To annoy, anger.What really pisses me off about my job is that I have to get up at six o'clock. •(informal, vulgar) To leave, to go away.They've pissed off and left us in the lurch!Why don't you piss off and leave us alone? exclamation1 •(Commonwealth, vulgar) Go away!Piss off, pal! This is my work table and yours is in the corner. formspissed off · pissing off · pisses off