perforation UK /ˌpəːfəˈreɪʃən/US /ˌpɚfəˈreɪʃən/ noun5 •Any opening in a solid object. •An abnormal opening in an organ, such as a rupture. •A series of holes punched through something in order to assist in separating parts. •The act of perforating or the state of being perforated. •That portion of a surface that remains after an open disk is removed from it. formsperforations