oocyst /ˈəʊəsɪst/ noun2 •A thick-walled spore in the lifecycle of some parasitic protozoans that develops into sporozoite.Ross had found in the stomach wall of an Anopheles mosquito the oocysts (eggs) which are the intermediate stage of the Plasmodium life cycle. — 1997 •(no longer used) A reproductive cell in certain fungi. formsoocysts