NPE noun3 •Initialism of null pointer exception. •Initialism of non-practicing entity.Therefore, arguably, the existence of NPEs helps facilitate and regulate supply and demand. — 2019 •Initialism of nonylphenol ethoxylate.The most important and commonly used APEs are nonylphenol ethoxylates (NPEs), which account for 80% of the APE market. — 2008 formsNPEs