nosocomial UK /ˌnɒ.sə(ʊ)ˈkəʊ.mi.əl/US /ˌnɑ.səˈkoʊ.mi.əl/ adjective2 •(formal) Of an infection or its cause: arising from the environment of, or treatment in, a hospital. •(formal) Of, relating to, or happening in a hospital.