moose knuckle noun3 •(slang) The noticeable shape of a man's penis when he is wearing tight clothes.[…]the VIP of the GOP, George W. Bush in full military flight suit, with his ejector harness giving him the worst moose knuckle in presidential history. — 2005 •(slang, nonstandard) The shape that is noticeable when tight-fitting clothing wedges between a woman's labia.I was grateful for the distraction, as I had been trying to look anywhere but at the giant moose knuckle spray-painted between her thighs […] — 2008 •The ball joint of the humerus in a moose's skeleton. formsmoose knuckles · moose-knuckles