Montezuma's revenge UK /ˌmɒn.təˈzuː.məz ɹɪˈvɛndʒ/US /ˌmɔ.ɾ̃əˈzu.məz ɹəˈvɛndʒ/ noun1 •(humorous, euphemistic) Diarrhea experienced by tourists after drinking water or eating food in Mexico as a result of a microorganism to which native Mexicans are immune.We warily sipped the lemonade, knowingly flirting with the tourist stomach disorder known here as Moctezuma's revenge. — 2010