Molossian noun 2adjective 1forms 3 noun2 •A member of the ancient Epirote ethnos which Olympias came from. •A breed of large dog of classical antiquity native to Epirus, resembling a mastiff and used as a hunting dog and guard dog.The hounds were Indian, Cretan or Locrian; there were also Molossians (mastiffs) and Spartans (big greyhounds). — 1975 adjective1 •Of or relating to Molossia or Molossians. formsMolossians · more Molossian · most Molossian