molly house noun1 •(historical) A tavern or other establishment in 18th and 19th century England where homosexuals could meet for various activities, such as cross-dressing and sexual encounters.In a vivid illustration of the dynamics created by sexual deviance, molly houses were a defense against the pressures of prejudice, but their visibility inspired new hostility. — 2007 formsMolly Houses · Molly houses · molly houses · molly-houses