mistressmind noun 1verb 1forms 3 noun1 •(nonstandard, rare) A female mastermind. verb1 •(nonstandard, rare) Of a woman: to mastermind.Moreover, he seems to be the man most likely to arrange for peace in our time, and therefore he is the constant prey of murderous villains who mistress[-]minded by a bosomy femme fatale (Daliah Lavi). — 1968 formsmistressminded · mistressminding · mistressminds