metoidioplasty UK /məˈtɔɪ.di.əʊˌplæs.ti/US /məˈtɔɪ.di.oʊˌplæs.ti/ noun1 •A form of female-to-male gender-affirming surgery in which the clitoris, enlarged by testosterone therapy, is enhanced in size and appearance to provide a penis. formsmetoidioplasties