Master of the Universe noun3 •GodConstantine inscribed these words on the pedestal:— Oh Christ! king and master of the universe, I consecrate this humble tower, this sceptre, and the power of Rome, to thee! — 1849 •A powerful person.First, by them made obstinate by the onetime masters of the universe. — 1557 •A highly successful business person.No matter how much you may dislike the Masters of the Universe, my friends, there are plenty of other parts of the universe that would welcome them. — 2008 formsMasters of the Universe