lose it verb7 •(informal) To be overcome with emotion. •(informal) To become explosively angry; to lose one's temper.When my dad found out I had failed the exams, he just lost it. •(informal) To feel devastated, or distraught, especially when one's sadness is overwhelming.When she heard the news about her cousin's death, she lost it. •(informal) To begin to laugh uncontrollably.When the teacher's chair broke, the class completely lost it. •(informal) To lose one's mind, go crazy. •To lose control of a situation.Even then, she defended everything she had sought to achieve, saying she had “the right policies at the wrong time”. “That’s when I thought ‘she’s totally lost it’,” said a former aide. — 2023 •(informal) To cease to have a skill or ability, to lose one's touch, to be washed up.When you think about all she's done for the sport, it's kind of sad, but she's completely lost it over the past few years. formslost it · losing it · loses it