ligation /lɪˈɡeɪʃən/ noun5 •The act of tying, of applying a ligature. •The state of having a ligature, of being tied. •The act of tying off or sealing a blood vessel, fallopian tube, etc during surgery; act of ligating. •Something that ties, a ligature. •The formation of a complex by reaction with a ligand. formsligations