least weasel /ˈliːst ˈwiːz(ə)l/ noun1 •The common weasel, little weasel, or simply weasel (Mustela nivalis), the smallest member of the weasel genus Mustela, native to Eurasia, North America, and North Africa.The range of the Least Weasel extends entirely across the continent on this hemisphere; but its north and south dispersion are less definite, in the present state of our knowledge. — 1877 formsleast weasels