hydrocodone /ˌhaɪ.dɹoʊˈkoʊˌdoʊn/ noun1 •A habit-forming compound that is derived from codeine and is administered in the form of its bitartrate C₁₈H₂₁NO₃·C₄H₆O₆ usually in combination with other drugs (as acetaminophen) as an analgesic or antitussive. formshydrocodones