hybridize /ˈhaɪ.bɹɪd.aɪz/ verb6 •To form a mixture of any kind. •To cross-breed animals or plants to form hybrids. •To produce hybrid offspring; to interbreed. •To construct a hybrid word from elements of different languages. •To combine atomic orbitals mathematically to form hybrid orbitals. •To combine complementary subunits of multiple biological macromolecules. formshybridized · hybridizing · hybridizes